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Notes on GLP-1s, muscle, and strength after 40.

Practical, research-backed writing on muscle preservation during weight loss, protein for adults 35 and over, and strength training that respects the body you have today.

GLP-1 muscle preservation

How to strength train on a GLP-1

Resistance training 2–3 times per week is the load-bearing intervention for keeping muscle on Ozempic, Wegovy, Mounjaro, or Zepbound. Here's the minimum effective routine, the research behind it, and how to progress without heavier weights.

GLP-1 muscle preservation

How much protein do I need on a GLP-1?

Most adults on Ozempic, Wegovy, or Mounjaro need around 1.0 gram of protein per pound of body weight to preserve muscle. Here's the research, the per-meal math, and how to actually hit it when appetite is suppressed.

GLP-1 muscle preservation

How much muscle do you lose on Ozempic?

Up to 40% of weight lost on Ozempic, Wegovy, or Mounjaro can be lean mass — meaning muscle and bone, not just fat. Here's the research, what it means in practice, and how to preserve muscle on a GLP-1.